Duocarmycin DM free base - CAS 1116745-06-2

Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) . Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.

DNA Alkylator/Crosslinker, ADC Cytotoxin

Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

1116745-06-2

C26H26ClN3O3

463.96

CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21

-20°C

Ice Packs

Small Compound