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Dutomycin - CAS 146663-67-4
Dutomycin - CAS 146663-67-4
SKU:MF-0126155-01
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Product Details
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Bioactivity
Dutomycin is a SERPINB6 inhibitor with a binding constant (KD) of 1.236 μM. It can induce autophagy and apoptosis in cancer cells and suppresses the growth of cancer cells in zebrafish xenotransplant models. Dutomycin holds potential for cancer research.
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Target
Autophagy, Apoptosis
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Related Pathways
Autophagy, Apoptosis
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CAS Number
146663-67-4
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Molecular Formula
C44H54O17
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Molecular Weight
854.889
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SMILES
O[C@]12[C@](O)(C(=O)C=3C(C1)=C(C)C4=C(C3O)C(=O)C=C(OC)C4=O)C(=O)C(C(C)=O)=C(O)[C@H]2O[C@@H]5O[C@H](C)[C@@H](O[C@H]6C[C@@](C)(O)[C@H](OC(/C(=C\[C@@H](CCC)C)/C)=O)[C@H](C)O6)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product