DX3-234 - CAS 2941323-59-5

DX3-234 is a potent oxidative phosphorylation (OXPHOS) inhibitor that acts by inhibiting complex I in the mitochondrial electron transport chain (ETC), leading to intracellular ATP depletion and cell death, and can be used for the treatment of specific cancers dependent on aerobic metabolism, such as pancreatic cancer.

OXPHOS, Mitochondrial Metabolism

Apoptosis, Metabolism

2941259

0.993

C25H35N5O6S2

565.71

C(C)(C)C=1N=C(ON1)N2CCN(C(=O)[C@H]3CN(S(=O)(=O)C4=CC=C(S(=O)(=O)C5CCC5)C=C4)CCC3)CC2

-20°C

Ice Packs

Small Compound