DYRK1-IN-1 - CAS 2814486-79-6

DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor that inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. It exhibits good permeability and cellular activity without P-glycoprotein liability, making it suitable for research on central nervous system penetrant DYRK1A chemical probes [1].

Others, DYRK

Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Others

2814401

C12H12N6

240.26

N(C)(C)C=1N=C(C2=C3N(N=C2)N=CC=C3)C=CN1

-20°C

Ice Packs

Small Compound