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Dyrk1A-IN-11 - CAS 3058626-26-6

Dyrk1A-IN-11 - CAS 3058626-26-6

MF-0142792-01

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Product Details

  • Bioactivity

    Dyrk1A-IN-11 (compound 166) is an effective inhibitor targeting dual-specificity tyrosine phosphorylation-regulated 1A (DYRK1A) with an EC50 of 0.0021 μM. Additionally, this compound inhibits the phosphorylation of Tau (Thr212) with an EC50 of 0.0361 μM.

  • Target

    DYRK

  • Related Pathways

    Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors

  • CAS Number

    3058594

  • Molecular Formula

    C23H23F5N8O

  • Molecular Weight

    522.47

  • SMILES

    FC=1C(=C2N(C1)N=C(N[C@H]3C(F)(F)CN(CC3)C4COC4)N=C2)C=5N=C6C(=CC5)N=C(C)N6CC(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound