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Molfinity

DZD1516 - CAS 2387570-00-3

DZD1516 - CAS 2387570-00-3

SKU:MF-0147110-01

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  • Bioactivity

    DZD1516, a potent and selective HER2 inhibitor (IC50 = 0.56 nM), demonstrates good blood-brain barrier permeability and exhibits antitumor activity in both central nervous system (CNS) and subcutaneous xenograft mouse models [1].

  • Target

    EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

  • CAS Number

    2387570-00-3

  • Molecular Formula

    C28H27F2N7O3

  • Molecular Weight

    547.56

  • SMILES

    O(C=1C=2C(NC3=CC(C)=C(OC4=CC=5N(C=C4)N=CN5)C=C3)=NC=NC2C=C(OC)C1)[C@@H]6C(F)(F)CN(C)CC6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound