(E/Z) -OT-R antagonist 1 - CAS 364076-99-3

(E/Z) -OT-R antagonist 1 is a mixture of the E/Z configurations of OT-R antagonist 1. This compound is a novel, potent, selective, non-peptide OT-R antagonist that inhibits oxytocin-induced intracellular Ca2+ activity with an IC50 of 8 nM.

Oxytocin Receptor

Endocrinology/Hormones, GPCR/G Protein

363974

C28H29N3O4

471.55

C(=O)(N1[C@H](C(NC[C@@H](O)C2=CC=CC=C2)=O)CC(=NOC)C1)C3=CC=C(C=C3)C4=C(C)C=CC=C4

-20°C

Ice Packs

Small Compound