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E3 ligase Ligand 10 - CAS 1073560-68-5
E3 ligase Ligand 10 - CAS 1073560-68-5
SKU:MF-0034878-01
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Product Details
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Bioactivity
E3 ligase Ligand 10 serves as a ligand for E3 ubiquitin ligase and can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. These PROTACs act as inducers of ubiquitination-mediated degradation, specifically targeting cancer-promoting proteins[1].
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Target
Others, Ligand for E3 Ligase
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Related Pathways
Others, PROTAC
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CAS Number
1073487
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Molecular Formula
C47H52N4O7
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Molecular Weight
784.94
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SMILES
C(OC(N([C@H](C(N[C@H](C(=O)N1[C@H](C(N[C@@H]([C@H](C2=CC=CC=C2)C3=CC=CC=C3)C(O)=O)=O)CCC1)C4CCCCC4)=O)C)C)=O)C5C=6C(C=7C5=CC=CC7)=CC=CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC