E3 ligase Ligand 18 - CAS 2241669-88-3

E3 ligase Ligand 18 is a small molecule ligand that specifically binds to E3 ubiquitin ligase, and E3 ligase Ligand 18 can be chemically linked to a protein-targeting ligand through a molecular linker to construct proteolysis-targeting chimeras (PROTACs), which subsequently induce ubiquitination-mediated degradation of disease-related proteins such as oncogenic factors, thereby supporting the study of targeted protein degradation in cancer biology.

Ligand for E3 Ligase

PROTAC

2241578

0.98125

C17H17ClN6O4S

436.87

C(N1C2=C(N=C1SC[C@H](NC(C)=O)C(O)=O)C(=O)N=C(N)N2)C3=CC=C(Cl)C=C3

-20°C

Ice Packs

PROTAC