E3 ligase Ligand 22 - CAS 2377849-57-3

E3 Ligase Ligand 22 (compound 139) serves as a cereblon binder, facilitating the degradation of Ikaros or Aiolos via the ubiquitin proteasome pathway [1].

Ligand for E3 Ligase

PROTAC

2377849-57-3

C28H34N6O4

518.61

N(CC1=CN(N=C1)C2CCN(CC3(C)CCC3)CC2)C4=C5C(C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=CC=C4

-20°C

Ice Packs

PROTAC