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E3 ligase Ligand-Linker Conjugate 39 - CAS 2632308-04-2
E3 ligase Ligand-Linker Conjugate 39 - CAS 2632308-04-2
SKU:MF-0120595-01
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Product Details
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Bioactivity
E3 ligase Ligand-Linker Conjugate 39, a conjugate of an E3 ligase ligand and linker, comprises Thalidomide and the corresponding Linker. This conjugate can act as a Cereblon ligand to recruit CRBN protein and serve as a crucial intermediate in the synthesis of complete PROTAC molecules.
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Target
E3 Ligase Ligand-Linker Conjugate
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Related Pathways
PROTAC
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CAS Number
2632308-04-2
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Molecular Formula
C25H31N5O6
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Molecular Weight
497.54
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SMILES
O=C1N(C(=O)C=2C1=CC(=CC2)N3CC(C3)N4CCN(C(OC(C)(C)C)=O)CC4)C5C(=O)NC(=O)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC