E3 Ligase Ligand-linker Conjugate 50 - CAS 2918813-56-4

E3 Ligase Ligand-linker Conjugate 50 comprises a VH032-based von Hippel-Lindau (VHL) ligand known as (S, R, S) -AHPC and a corresponding linker. This conjugate specifically involves the combination of an E3 ligase ligand and a linker, where (S, R, S) -AHPC functions to recruit VHL proteins. It serves as a crucial intermediate in synthesizing complete PROTAC molecules.

E3 Ligase Ligand-Linker Conjugate

PROTAC

2918813-56-4

C33H47N5O6S

641.82

C([C@@H](NC(=O)C1CCN(C(OC(C)(C)C)=O)CC1)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2

-20°C

Ice Packs

PROTAC