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E3 Ligase Ligand-linker Conjugate 91 - CAS 2229713-40-8
E3 Ligase Ligand-linker Conjugate 91 - CAS 2229713-40-8
SKU:MF-0120604-01
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Product Details
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Bioactivity
E3 Ligase Ligand-linker Conjugate 91, a conjugate of an E3 ligase ligand and linker, consists of (S, R, S) -AHPC and the corresponding linker. (S, R, S) -AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. This conjugate serves as a key intermediate for synthesizing complete PROTAC molecules.
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Target
E3 Ligase Ligand-Linker Conjugate
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Related Pathways
PROTAC
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CAS Number
2229713-40-8
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Molecular Formula
C35H52N6O7S
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Molecular Weight
700.89
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SMILES
C([C@@H](NC(COCCN1CCN(C(OC(C)(C)C)=O)CC1)=O)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC