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Molfinity

E3 ligase Ligand PG - CAS 14149-34-9

E3 ligase Ligand PG - CAS 14149-34-9

SKU:MF-0121840-01

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  • Bioactivity

    E3 Ligase Ligand PG serves as an E3 ligase ligand capable of recruiting the CRBN protein. It demonstrates strong binding affinity with CRBN, exhibiting an IC50 of 2.191 μM. Furthermore, E3 Ligase Ligand PG can be linked via a linker to BMS-202 to form PROTAC, PROTACPD-L1degrader-1.

  • Target

    Ligand for E3 Ligase

  • Related Pathways

    PROTAC

  • CAS Number

    14149-34-9

  • Molecular Formula

    C11H11NO2

  • Molecular Weight

    189.21

  • SMILES

    O=C1NC(=O)C(C=2C=CC=CC2)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC