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E3 ligase Ligand PG - CAS 14149-34-9
E3 ligase Ligand PG - CAS 14149-34-9
SKU:MF-0121840-01
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Product Details
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Bioactivity
E3 Ligase Ligand PG serves as an E3 ligase ligand capable of recruiting the CRBN protein. It demonstrates strong binding affinity with CRBN, exhibiting an IC50 of 2.191 μM. Furthermore, E3 Ligase Ligand PG can be linked via a linker to BMS-202 to form PROTAC, PROTACPD-L1degrader-1.
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Target
Ligand for E3 Ligase
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Related Pathways
PROTAC
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CAS Number
14149-34-9
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Molecular Formula
C11H11NO2
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Molecular Weight
189.21
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SMILES
O=C1NC(=O)C(C=2C=CC=CC2)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC