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Molfinity

E7449 - CAS 1140964-99-3

E7449 - CAS 1140964-99-3

MF-0093570-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.

  • Target

    PARP

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    1140862

  • Purity

    0.97816

  • Molecular Formula

    C18H15N5O

  • Molecular Weight

    317.34

  • SMILES

    O=c1[nH][nH]c2nc(CN3Cc4ccccc4C3)nc3cccc1c23

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound