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EA-B2L - CAS 1354444-72-6
EA-B2L - CAS 1354444-72-6
SKU:MF-0110739-01
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Product Details
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Bioactivity
EA-B2L is an effective degrader of glutathione S-transferase (GSTP) with a DC50 of 48 μM. It is composed of Ethacrynic acid linked to Boc2Lys. EA-B2L plays a significant role in cancer research.
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Target
E1/E2/E3 Enzyme, Ligand for E3 Ligase
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Related Pathways
Ubiquitination, PROTAC
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CAS Number
1354366
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Molecular Formula
C35H54Cl2N4O8
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Molecular Weight
729.73
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SMILES
C(C(CC)=C)(=O)C1=C(Cl)C(Cl)=C(OCC(NCCCCCCNC([C@@H](NC(OC(C)(C)C)=O)CCCCNC(OC(C)(C)C)=O)=O)=O)C=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound