EAPB-0503 - CAS 1140627-77-5

EAPB-0503, an imidazoquinoxaline derivative and an analog of Imiquimod, selectively reduces HDM2 expression and activates the p53 pathway in cells expressing NPM1c, thereby inducing apoptosis.

Apoptosis, PARP, Bcr-Abl

Chromatin/Epigenetic, Angiogenesis, Apoptosis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair

1140545

C18H16N4O

304.35

N=1C=C(C2=CC=CC(OC)=C2)N3C1C(=NC=4C=CC=CC43)NC

-20°C

Ice Packs

Small Compound