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Ebselen derivative 1 - CAS 3030492-59-9
Ebselen derivative 1 - CAS 3030492-59-9
SKU:MF-0147509-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Ebselen derivative 1 (Compound 19), an orally active glutathione peroxidase (GPx) mimic, exhibits notable protective effects against cisplatin-induced hair cell (HC) damage in both in vitro and in vivo settings. It significantly reduces oxidative stress, apoptosis, and ferroptosis in hair cells, making it useful in the study of cisplatin-induced hearing loss [1].
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Target
Apoptosis, Ferroptosis
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Related Pathways
Apoptosis
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CAS Number
3030492-59-9
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Molecular Formula
C13H10N2O2Se
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Molecular Weight
305.19
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SMILES
O(C)C1=C2C(C(=O)N([Se]2)C=3C=CC=NC3)=CC=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound