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Molfinity

Echistatin - CAS 154303-05-6

Echistatin - CAS 154303-05-6

SKU:MF-0153293

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  • Bioactivity

    Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM) . Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM) . Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro.

  • Target

    Integrin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    154303-05-6

  • Molecular Formula

    C217H341N71O74S9

  • Molecular Weight

    5417.1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide