Ecopipam - CAS 112108-01-7

Ecopipam (UNII-0X748O646K) is a potent, selective, and orally active antagonist of dopamine D1/D5 receptors, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam demonstrates more than 40-fold selectivity over D2, D4, 5-HT, and α2a receptors (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively) . It is used in research on schizophrenia and obesity.

5-HT Receptor, Dopamine Receptor, Adrenergic Receptor

GPCR/G Protein, Neuroscience

112108-01-7

0.9968

C19H20ClNO

313.82

CN1[C@@]2([C@@](C=3C(=CC(Cl)=C(O)C3)CC1)(C=4C(CC2)=CC=CC4)[H])[H]

-20°C

Ice Packs

Small Compound