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Edatrexate - CAS 80576-83-6
Edatrexate - CAS 80576-83-6
SKU:MF-0143470-01
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Product Details
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Bioactivity
Edatrexate (CGP 30694), also known as 10-Ethyl-10-deazaaminopterin, is an analog of Methotrexate that demonstrates antitumor activity against Methotrexate-resistant tumors. This antifolate antimetabolite is utilized in research related to non-small-cell lung cancer, breast cancer, non-Hodgkin's lymphoma, and head and neck cancer [1] [2].
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Target
Others, Antifolate
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Related Pathways
Cell Cycle/Checkpoint, Others
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CAS Number
80487
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Molecular Formula
C22H25N7O5
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Molecular Weight
467.48
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SMILES
NC=1C2=C(N=CC(CC(CC)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)N=C(N)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound