EED-IN-3 - CAS 3051817-48-9

EED-IN-3 is an orally active inhibitor of EED. It effectively binds with EED (IC50 = 0.62 μM) to inhibit PRC2 and reduces H3K27me3 levels. EED-IN-3 selectively inhibits PC3 cells with an IC50 of 3.69 μM and significantly suppresses colony formation and migration. This compound is useful for prostate cancer research.

Histone Methyltransferase, Epigenetic Reader Domain

Chromatin/Epigenetic

3051760

C25H29N3O5

451.52

O=C(NCCCOC(C)C)C1=CC(=NN(C1=O)C2=CC=C(OC)C=C2)C=3C=CC(OC)=CC3

-20°C

Ice Packs

Small Compound