EF24 - CAS 342808-40-6

EF24 (3,5-Bis[ (2-fluorophenyl) Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.

Apoptosis, NF-κB, Caspase, p38 MAPK, ERK, MEK, ROS

Proteases/Proteasome, Immunology/Inflammation, Apoptosis, NF-κB, MAPK

342762

>99.99%

C19H15F2NO

311.33

Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O

-20°C

Ice Packs

Small Compound