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EFdA-TP - CAS 950913-56-1
EFdA-TP - CAS 950913-56-1
SKU:MF-0039704
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Product Details
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Bioactivity
EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways.
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Target
Reverse Transcriptase, HIV Protease, Others, DNA/RNA Synthesis
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Related Pathways
Proteases/Proteasome, Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair, Others
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CAS Number
950856
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Molecular Formula
C12H15FN5O12P3
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Molecular Weight
533.195
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SMILES
Nc1nc(F)nc2n(cnc12)[C@H]1C[C@H](O)[C@@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O1)C#C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound