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Efflux inhibitor-1 - CAS 1776055-29-8

Efflux inhibitor-1 - CAS 1776055-29-8

SKU:MF-0146220-01

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  • Bioactivity

    Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC 50 s of 0.45 μM and 2.17 μM, respectively .

  • Target

    Others, BCRP

  • Related Pathways

    Others, Membrane transporter/Ion channel

  • CAS Number

    1776018

  • Molecular Formula

    C28H25N5O3

  • Molecular Weight

    479.53

  • SMILES

    O(C)C1=C(C2=NN3C(=CC(=NC3=C2)C4=CC=CC=C4)N5CCN(C(=O)C=6C=COC6)CC5)C=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound