EGFR/C797S-IN-1 - CAS 2378188-21-5

EGFR/C797S-IN-1 is a potent inhibitor targeting the EGFR-C797S mutation, with an IC50 value of 0.128 μM, exhibiting significant anti-proliferative and anti-tumor effects by inhibiting p-EGFR expression in a dose-dependent manner.

Others, EGFR

Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Others

2378162

C28H30N4O3

470.56

N(C=1C2=C(C=C(OCC3CCN(C)CC3)C(OC)=C2)N=CN1)C4=CC=C(OC5=CC=CC=C5)C=C4

-20°C

Ice Packs

Small Compound