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EGFR/HER2/CDK9-IN-2 - CAS 1180924-34-8

EGFR/HER2/CDK9-IN-2 - CAS 1180924-34-8

SKU:MF-0139756-01

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  • Bioactivity

    EGFR/HER2/CDK9-IN-2 are potent inhibitors of EGFR/HER2/CDK9, and they exhibited significant antitumor effects with IC50s of 145.35, 129.07 and 117.13 nM, respectively.

  • Target

    Others, EGFR, CDK

  • Related Pathways

    JAK/STAT signaling, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Others, Angiogenesis

  • CAS Number

    1180882

  • Molecular Formula

    C23H20N4O5S2

  • Molecular Weight

    496.56

  • SMILES

    C(CC1=CC=C(S(N)(=O)=O)C=C1)N2C(SCC3=CC=C(N(=O)=O)C=C3)=NC=4C(C2=O)=CC=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound