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EGFR/HER2/CDK9-IN-2 - CAS 1180924-34-8
EGFR/HER2/CDK9-IN-2 - CAS 1180924-34-8
SKU:MF-0139756-01
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$1,383.80 USD
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Product Details
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Bioactivity
EGFR/HER2/CDK9-IN-2 are potent inhibitors of EGFR/HER2/CDK9, and they exhibited significant antitumor effects with IC50s of 145.35, 129.07 and 117.13 nM, respectively.
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Target
Others, EGFR, CDK
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Related Pathways
JAK/STAT signaling, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Others, Angiogenesis
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CAS Number
1180882
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Molecular Formula
C23H20N4O5S2
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Molecular Weight
496.56
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SMILES
C(CC1=CC=C(S(N)(=O)=O)C=C1)N2C(SCC3=CC=C(N(=O)=O)C=C3)=NC=4C(C2=O)=CC=CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound