EGFR/HER2/CDK9-IN-3 - CAS 422276-47-9

EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR (IC50:191.08 nM), HER2 (IC50:132.65 nM), and CDK9 (IC50:113.98 nM), demonstrating significant anti-tumor effects.

CDK, Others, EGFR

JAK/STAT signaling, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Others, Angiogenesis

422220

C24H21N3O4S2

479.57

C(CC1=CC=C(S(N)(=O)=O)C=C1)N2C(SCC(=O)C3=CC=CC=C3)=NC=4C(C2=O)=CC=CC4

-20°C

Ice Packs

Small Compound