EGFR/HER2-IN-10 - CAS 2931499-82-8

EGFR/HER2-IN-10 (compound 9F) serves as a potent, selective dual inhibitor for EGFR and HER2, exhibiting IC50 values of 2.3 nM for EGFR and 234 nM for HER2. Additionally, it demonstrates effective antiproliferative activity against prostate carcinoma [1].

EGFR

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

2931499-82-8

C29H24ClF3N6O5

628.99

N(C=1C2=C(C=C(OC)C(OCCCCN3C(N(=O)=O)=NC=C3)=C2)N=CN1)C4=CC(Cl)=C(OC5=CC(C(F)(F)F)=CC=C5)C=C4

-20°C

Ice Packs

Small Compound