EGFR/HER2-IN-9 - CAS 1637253-79-2

EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR T790M mutation.

EGFR, Others

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling, Others

1637172

C25H25ClFN5O4

513.95

N(C=1C2=C(C=C(OC)C(NC(/C=C/CN3C[C@@]4([C@](C3)(OCCO4)[H])[H])=O)=C2)N=CN1)C5=CC(Cl)=C(F)C=C5

-20°C

Ice Packs

Small Compound