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Molfinity

EGFR-IN-104 - CAS 2758904-45-7

EGFR-IN-104 - CAS 2758904-45-7

MF-0147528-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    EGFR-IN-104 (Compound A23) acts as a potent EGFR inhibitor, demonstrating IC50 values of 0.33 μM for EGFR L858R/T790M and 0.133 μM for EGFR Del19/T790M/C797S. It exhibits anticancer properties, effective both in vitro and in vivo [1].

  • Target

    EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

  • CAS Number

    2758904-45-7

  • Molecular Formula

    C23H27N7OS

  • Molecular Weight

    449.57

  • SMILES

    OC1=C(C2=NC(NCC=3C=NC(=NC3)N4CCN(C)CC4)=C5C(=N2)CCSC5)C=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound