EGFR-IN-109 - CAS 3019971-97-9

EGFR-IN-109 (compound 4), an EGFR inhibitor, displays IC 50 values of 25.8 nM for EGFR WT and 182.3 nM for EGFR T790M. This compound halts the growth of cancer cells at the G2/M phase and triggers both early and late apoptosis. It is applicable in cancer research [1].

Apoptosis, Caspase, Bcl-2 Family, EGFR

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Proteases/Proteasome, Apoptosis

3019971-97-9

C12H16N4OS

264.35

O=C1C=2C3=C(SC2NC(CNN)=N1)CC(C)CC3

-20°C

Ice Packs

Small Compound