EGFR-IN-112 - CAS 2758436-98-3

EGFR-IN-112 (SPP10), an EGFR kinase inhibitor, displays IC50 values of 2.31 ± 0.3 μM for MCF-7, 3.16 ± 0.8 μM for H69AR, and 4.2 ± 0.2 μM for PC-3 cancer cells, showcasing selective cytotoxicity towards these cancer cell lines.

EGFR

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

2758436-98-3

C27H23N3S

421.56

N=1N=C(C2=CC=CC=C2)C3=C(C1C=4C=CC=CC4)C(=NC35CCCCC5)C6=CSC=C6

-20°C

Ice Packs

Small Compound