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EGFR-IN-146 - CAS 166039-38-9
EGFR-IN-146 - CAS 166039-38-9
SKU:MF-0114225-01
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Product Details
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Bioactivity
EGFR-IN-146 is an EGFR inhibitor that suppresses the EGFR signaling pathway and improves insulin sensitivity by activating the AMPK pathway. It effectively reduces blood glucose levels and body weight, showing great potential in the study of diabetes and obesity.
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Target
AMPK, EGFR
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Related Pathways
Angiogenesis, JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling
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CAS Number
165992
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Molecular Formula
C20H16N4
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Molecular Weight
312.368
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SMILES
N=1C=CC=C(C1)CNC=2N=C(N=C3C=CC=CC32)C=4C=CC=CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound