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EGFR-IN-157 - CAS 3061364-63-1
EGFR-IN-157 - CAS 3061364-63-1
SKU:MF-0115491-01
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Product Details
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Bioactivity
EGFR-IN-157 (compound IIB-5) is a potent EGFR inhibitor with an IC50 of 18.81 nM and is applicable for research in non-small cell lung cancer (NSCLC) .
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Target
EGFR
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Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
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CAS Number
3061300
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Molecular Formula
C28H39N9O3S
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Molecular Weight
581.73
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SMILES
O=S(=O)(NC=1C=NN(C1)C2=NC(=NC=C2)NC=3C=C(C(=CC3OC)N4CCC(N5CCN(C)CC5)CC4)C)C6CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound