EGFR-IN-166 - CAS 503443-98-9

EGFR-IN-166 (Compound 2) is an EGFR inhibitor demonstrating potent anticancer activity against breast cancer cells, with an IC50 of 69.63 μM for MCF-7 cells and 22.84 μM for MDA-MB-231 cells. It notably inhibits cell migration and EGFR expression, making it valuable for breast cancer research.

EGFR

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

503336

C19H15N3O2S

349.41

O=C1SC(=C2C(=O)N(N=C2C)C=3C=CC=CC3)N(C=4C=CC=CC4)C1

-20°C

Ice Packs

Small Compound