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EGFR-IN-22 - CAS 2634646-14-1

EGFR-IN-22 - CAS 2634646-14-1

MF-0154613-01

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Product Details

  • Bioactivity

    EGFR-IN-22 is a highly effective inhibitor targeting wild type EGFR and its mutant form, EGFR L858R/T790M/C797S, displaying IC50 values of 4.91 nM and 0.54 nM, respectively.

  • Target

    Others, EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Others, Angiogenesis, JAK/STAT signaling

  • CAS Number

    2634631

  • Molecular Formula

    C38H47BrFN10O2P

  • Molecular Weight

    805.72

  • SMILES

    COc1cc(N2CCC3(CC2)CCN(CC3)C(C)(C)CF)c(cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)-c1cnn(C)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound