EGFR-IN-23 - CAS 2747133-37-3

EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.05 nM against the BaF3/EGFR-DEL19/T790M/C797S cell line.

EGFR, Others

JAK/STAT signaling, Others, Angiogenesis, Tyrosine Kinase/Adaptors

2747093

C36H44BrN10O3P

775.68

N(C1=CC(=C(C=C1OC)N2CCC(CN3CCCOCC3)CC2)C=4C=NN(C)C4)C=5N=C(NC6=C(P(C)(C)=O)C7=C(C=C6)N=CC=N7)C(Br)=CN5

-20°C

Ice Packs

Small Compound