EGFR-IN-33 - CAS 2711105-59-6

EGFR-IN-33, an acrylamide derivative, is a low-toxicity antitumor agent and a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-33 exhibits potential for the study of EGFR mutation-related diseases.

EGFR, Others

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Others

2711040

C26H25ClN6O2

488.97

NC1=C2N(C=C(C2=NC=N1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4

-20°C

Ice Packs

Small Compound