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Molfinity

EGFR-IN-36 - CAS 2711105-54-1

EGFR-IN-36 - CAS 2711105-54-1

SKU:MF-0040439-01

Regular price $1,383.80 USD
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  • Bioactivity

    EGFR-IN-36 is a potent inhibitor of EGFR, acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), and HER2 (A775_G776insYVMA) (IC50: 2.35 nM) . EGFR-IN-36 exhibits potential for studying wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.

  • Target

    Others, EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Others, Angiogenesis

  • CAS Number

    2711050

  • Molecular Formula

    C26H25ClN6O2

  • Molecular Weight

    488.97

  • SMILES

    NC=1C2=C(C=C(N2N=CN1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound