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EGFR-IN-38 - CAS 2711105-50-7

EGFR-IN-38 - CAS 2711105-50-7

SKU:MF-0039774-01

Regular price $1,383.80 USD
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  • Bioactivity

    EGFR-IN-38 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-38 exhibits potential for research in EGFR mutation-related diseases.

  • Target

    Others, EGFR

  • Related Pathways

    JAK/STAT signaling, Others, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    2711048

  • Molecular Formula

    C25H24ClN7O2

  • Molecular Weight

    489.96

  • SMILES

    NC1=C2N(N=C(C2=NC=N1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound