EGFR-IN-49 - CAS 2459932-81-9

EGFR-IN-49 is a potent and selective EGFR inhibitor that targets EGFRT790M (IC50: 65.0 nM) and EGFRT790M/L858R (IC50: 13.6 nM), inducing apoptosis in a dose-dependent manner.

Others, EGFR

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Others

2459842

C22H15N5O2S

413.45

O(C1=C2C(=NC(NC3=CC(C#N)=CC=C3)=N1)C=CS2)C4=CC(NC(C=C)=O)=CC=C4

-20°C

Ice Packs

Small Compound