EGFR-IN-50 - CAS 2044508-48-5

EGFR-IN-50 is a potent EGFR inhibitor targeting L858R resistance mutations, acting on TEL-EGFR-L858R-BaF3 and TEL-EGFR-T790M-L858R-BaF3 with GI50 values of 8 nM and 6.03 μM, respectively. EGFR-IN-50 exhibits anti-proliferative effects on cancer cells. .

Others, EGFR

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Others, Angiogenesis

2044455

C24H26BrN3O4S2

564.51

N(C=1C2=C(C=C(OCCCOC(CCSSCC=C)=O)C(OC)=C2)N=CN1)C3=CC(Br)=CC=C3

-20°C

Ice Packs

Small Compound