EGFR-IN-51 - CAS 2418549-32-1

EGFR-IN-51 (Compound 6) is a highly potent EGFR inhibitor with IC50 values of 0.493, 102.60, and 461.63 μM against EGFR, EGFR L858R-TK, and EGFR T790M-TK targets, respectively. Additionally, EGFR-IN-51 exhibits cytotoxicity against cancer cell lines, effectively inducing apoptosis [1].

Others, Apoptosis, EGFR

Apoptosis, Others, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

2418549-32-1

C21H15N3O2S

373.43

N(C(NC=1C=C2C(=CC1)OCO2)=S)C=3C4=C(N=C5C3C=CC=C5)C=CC=C4

-20°C

Ice Packs

Small Compound