EGFR-IN-55 - CAS 2057423-46-6

EGFR-IN-55 is a potent inhibitor of EGFR, acting on EGFRWT (IC50: 70 nM) and EGFRL858R/T790M (IC50: 3.9 nM) . EGFR-IN-55 was able to block the cell cycle of NCI-H1975 cells in G0/G1 phase, exhibiting anticancer effects.

EGFR, Others

JAK/STAT signaling, Others, Angiogenesis, Tyrosine Kinase/Adaptors

2057371

C25H25Cl2N7O2

526.42

N(C1=CC=C(C=C1)N2CCN(C(C)=O)CC2)C=3N=C(NC4=CC(NC(C(=C)Cl)=O)=CC=C4)C(Cl)=CN3

-20°C

Ice Packs

Small Compound