EGFR-IN-69 - CAS 2433837-65-9

EGFR-IN-69 is a potent inhibitor of the EGFR enzyme, demonstrating IC50 values of 4.3 nM for EGFR L858R/T790M/C797S, 6.6 nM for EGFR L858R/T790M, and 25.6 nM for EGFR 19del/T790M/C797S. This compound is utilized in the research of non-small-cell lung cancer (NSCLC) .

Others, EGFR

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Others

2433763

C31H37Cl2N7O3S

658.64

ClC=1C(C=2C=3C(N(S(CC)(=O)=O)C2)=CC=CC3)=NC(NC4=C(OC)C=C(C(Cl)=C4)N5CCC(CC5)N6CCN(C)CC6)=NC1

-20°C

Ice Packs

Small Compound