EGFR-IN-88 - CAS 2944452-34-8

EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis [1].

Apoptosis, EGFR

Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

2944410

C22H18Cl2N4O2S

473.37

C(C)C1=NC2=C(N=C1CC)C=CC(=C2)C=3OC(SCC(=O)C4=C(Cl)C=C(Cl)C=C4)=NN3

-20°C

Ice Packs

Small Compound