EGFR-IN-9 - CAS 1226549-39-8

EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M) . EGFR-IN-9 has antitumor activity.

EGFR

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

1226502

0.998

C29H24N4O3

476.53

OC[C@@H](Nc1ncnc2oc(c(-c3cccc(NC(=O)C=C)c3)c12)-c1ccccc1)c1ccccc1

-20°C

Ice Packs

Small Compound