EGFR ligand-2 - CAS 2737283-20-2

EGFR ligand-2 (compound C4) is a covalent EGFR ligand and mutant inhibitor with IC50 values of 21 nM for EGFR L858R and 48 nM for EGFR L858R/T790M. It can be utilized in the synthesis of PROTAC [1].

EGFR

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

2737283-20-2

C30H35N9O

537.66

N(C=1N(C=2C(N1)=CN=C(NC3=CC=C(C=C3)N4CCN(C)CC4)N2)[C@@H]5CN(C(C=C)=O)CCC5)C6=CC=CC=C6

-20°C

Ice Packs

Small Compound