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EGFR T790M/L858R-IN-8 - CAS 333419-97-9

EGFR T790M/L858R-IN-8 - CAS 333419-97-9

MF-0147922-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    333419-97-9

  • Molecular Formula

    C16H11BrN2O3

  • Molecular Weight

    359.17

  • SMILES

    O=C(NC=1C=CC=C(Br)C1)C=2C(=O)NC=3C=CC=CC3C2O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound